MALAN SYNDROME (SOTOS SYNDROME 2) IN TWO PATIENTS WITH 19P13.2 DELETION ENCOMPASSING NFIX GENE AND NOVEL NFIX SEQUENCE VARIANT

Malan syndrome (Sotos syndrome 2) in two patients with 19p13.2 deletion encompassing NFIX gene and novel NFIX sequence variant

Background and Aim.Sotos syndrome 2 (MIM #614753), known also as Malan syndrome, is caused by heterozygous mutations/deletions of the NFIX gene located on chromosome 19p13.2.It manifests in developmental delay, intellectual impairment, macrocephaly, central nervous system anomalies, postnatal overgrowth, and craniofacial dysmorphism.Unusual behavio

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A new fossil cricket of the genus Proanaxipha in Miocene amber from the Dominican Republic (Orthoptera, Gryllidae, Pentacentrinae)

Unframed Baseball Photos A new species of the cricket genus Proanaxipha Vickery & Poinar (Orthoptera: Gryllidae: Pentacentrinae) from Early Miocene Dominican amber is described and illustrated.Proanaxipha madgesuttonae sp.n.is distinguished from congeners by: (1) head capsule bearing a distinctive posteriorly bilobed colour spot on the vertex;

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